Name: Immunokun (dogs - 270 g) Immune Response Enhancement Supplement
Brand: KUNKAY
SKU: 11051
Price: 3129 EUR
Availability: InStock

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Composition

Ingredients

Yeast products (mannanoligosaccharides - 15.6%, beta-glucans - 4.2%), fructooligosaccharides, flavoring by-product (hydrolyzed liver from pork and chicken), dried leaves of Artemisia annua (from organic farming, 4.2%).

Nutritional Additives

Aromas: L-glutamic acid - 222,220 mg/kg; Intestinal flora stabilizers: Enterococcus faecium - 1.1 × 10^11 CFU/kg; Vitamins: Vitamin C - 4,400 mg/kg, Vitamin E - 33,330 IU/kg; Trace elements: Zinc (zinc glycinate chelate) - 2,222 mg/kg, Selenium (sodium selenite) - 7.8 mg/kg.

Analytical Components

Crude protein 38.63%; Crude fiber 2.86%; Crude fat 6.81%; Crude ash 9.50%

How do its active ingredients work?

Beta-glucans

Beta-glucans are Pathogen Associated Molecular Patterns (PAMPs) molecules that act as modifiers of the immune response. They activate local macrophages and dendritic cells to positively regulate MHC class II and increase the secretion of cytokines (TNF-α, IL-2, IL-10, and IL-12), allowing them to efficiently present antigens to T lymphocytes and initiate an effective immune response. Beta-glucans stimulate a new concept called trained immunity or innate immune memory, which allows macrophages, monocytes, and natural killer cells to exhibit enhanced responsiveness when encountering pathogens again, both at the digestive and systemic levels.

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Artemisia annua

It provides a dual protective action against the protozoan Leishmania infantum. 1: It exhibits leishmanicidal action (apoptotic antileishmanial activity); 2: It preferentially stimulates Th1 immunity (characterized by increased levels of IFN-γ, CD4+ and CD8+ T lymphocytes, and nitrite) and suppresses Th2 immune responses with reduced levels of IL-4 and IL-10.

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L-glutamic acid

Precursor de la glutamina, considerado un aminoácido condicionalmente esencial y un nutriente clave para el correcto funcionamiento del sistema inmunitario. La glutamina es la fuente energética preferida para las células inmunitarias y proporcionar mayores cantidades de este nutriente esencial mejora su funcionamiento.

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Enterococcus faecium

Encapsulated probiotic (technology that ensures bacterial stability during the manufacturing and product storage period). Enterococcus faecium modifies the immune response through two mechanisms. 1: Indirectly due to its ability to balance the intestinal microbiota. Competition for nutrients, adhesion sites, and the production of antimicrobial substances (short-chain fatty acids, defensins, etc.) inhibit the proliferation of pathogenic bacteria while promoting the growth of beneficial bacteria; 2: Direct effect on both innate and acquired immune responses to pathogens locally and systemically. Probiotics induce the maturation of dendritic cells and macrophages (increasing their phagocytic activity and antigen presentation efficiency to T lymphocytes), promote the production of cytokines (TNF-α and IL-6), stimulate the cellular activity of natural killer cells, and enhance vaccination response (increased production of IgG and IgA).

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Mannanoligosaccharides

They increase the secretion of IgA in the intestine, stimulating the most important humoral immune factor of the intestinal mucosa. They inhibit the adherence, colonization, and penetration of bacteria and toxins, increase mucus secretion, and prevent the uptake of food antigens. In this regard, the increase in IgA at the intestinal level represents greater local immune capacity and greater protection against pathogen invasion.

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Fructooligosaccharides

Fructooligosaccharides are a prebiotic component, meaning they resist digestion and reach the colon intact, where they serve as a source of energy. This promotes the proliferation of beneficial bacteria (Lactobacillus spp, Bacteroides spp, and Bifidobacterium spp), which inhibit the growth of pathogenic bacteria through exclusive competition. Additionally, as a result of their fermentation, they increase the release of short-chain fatty acids (acetate, propionate, lactate, and butyrate) into the intestinal lumen, reducing the presence of pathogenic bacteria (such as E. coli and C. perfringens) by lowering the colonic pH.

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Vitamin E

Immune cells contain particularly high concentrations of vitamin E to protect themselves from oxidative damage associated with their high metabolic activity and the high content of polyunsaturated fatty acids in their plasma membrane. Vitamin E enhances the integrity of the cell membrane and positively modulates signaling events in T lymphocytes. Additionally, indirectly, vitamin E protects T cell function by reducing the production of T cell suppressor factors such as PGE2 produced by macrophages.

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Vitamin C

It is the most potent reducing agent available for cells. Vitamin C regenerates the enzyme glutathione, neutralizes free radicals both intra- and extracellularly, and protects against protein inactivation mediated by free radicals associated with oxidative burst in neutrophils.

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Selenium

It acts as a cofactor for glutathione peroxidase, an antioxidant enzyme that protects tissues against oxidative stress by catalyzing the reduction of hydrogen peroxides and organic hydroperoxides and regenerating vitamin E.

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Zinc

Zinc increases the activity of antioxidant enzymes such as glutathione peroxidase and is a cofactor of the enzyme superoxide dismutase, which catalyzes the conversion of superoxide radicals into H2O2, less oxidizing agents. Zinc deficiency causes dysfunction in almost all classes of immune cells and is also related to thymus involution.

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To whom and for what purpose?

Immunokun prevents the onset of infections and improves the health of healthy animals with low defenses such as puppies from weaning to 6 months of age, elderly animals (around five years in large or giant breed dogs and around seven years in small dogs), obese dogs, animals with a high level of physical activity, furry pets under conditions of chronic stress, or lactating females.

In dogs positive for Leishmania or diagnosed with other infectious diseases such as parvovirus, ehrlichiosis, scabies, ringworm, or infectious processes of the skin and respiratory system, Immunokun reduces symptoms and slows the progression of these infections, improving the quality of life of your dog.
In case of other diseases that involve immunosuppression such as Cushing's Syndrome, Immunokun prevents the onset of secondary infections, improving your pet's health.
During any vaccination, Immunokun enhances the immune system response to vaccination, making it more effective and ensuring better protection for your dog.

IMMUNOKUN is not recommended for use in case of:

Patients with allergies (whether food allergies or environmental allergies, flea bite allergies, drug allergies, etc.)
Patients with acute or chronic systemic inflammatory processes such as arthritis, dermatitis, enteritis, hepatitis, pancreatitis, etc.
Autoimmune diseases such as Addison's disease, pemphigus, lupus erythematosus, rheumatoid arthritis, glomerulonephritis and meningoencephalitis of the immune complex, myositis, etc.
Animals undergoing chemotherapy or concurrent use with pro-oxidant drugs, as Immunokun's antioxidant effect could reduce their effectiveness.
Patients with epilepsy or gastritis.
Pregnant or lactating females.

How is it administered?

Daily recommendation to be added on top of the food. This dose can be divided into different servings throughout the day:

Weight	Tablespoons*	Duration of the container
<10 kg	0.5	2 months
10-20 kg	1.0	1 month
20-30 kg	1.5	20 days
>30 kg	2.0	15 days

*9.1 g per tablespoon. The spoon is included in the container.

Immunokun for dogs can be administered concurrently with any type of diet (dry, homemade or commercial cooked, BARF or dehydrated). Additionally, it can be administered chronically without the need for any rest period between containers.

How long should I administer it?

Healthy animals with low defenses (puppies, senior animals, athletic dogs, obese animals, lactating females, etc.): Administer half of the recommended daily dose as preventive treatment.
Dogs positive for Leishmania or diagnosed with other infectious diseases: Administration is recommended for at least 1 month and to be maintained while symptoms persist.
Other diseases involving immunosuppression: Administration is recommended for at least 1 month and to be maintained while symptoms persist.
During any vaccination: 5 days before vaccination, on the day of vaccination, and for the following 7 days.

Perfecto!

Very happy with product and so are my dogs. I prefer this more than the pill form because it is more natural and my dogs love the taste. Muchas gracias!

¡Genial! Lo combino con Supergreenkun

No es el primer ni último producto de KUNKAY que uso con mis mascotas. A los peludos les encanta, lo utilizo para hacer recetas y me ahorro siempre un 10% usando el código KUNKAYRECETASBARF ¡Recomendado!

Hola, estoy muy contenta tanto con el producto como con el trato ya que me han respondido rápido a cualquier duda que tenia.
Le compré este suplemento a mi cachorra debido a que se estaba tratando de moquillo, a parte de sus tratamiento, le vino muy bien este aporte de más para su sistema inmunitario, se le va notando su mejoría y es muy fácil de proporcionárselo.
Lo recomiendo 😊

Immunokun (perros – 270 g) Suplemento para Mejorar la Respuesta inmunitaria

INNOVACIÓN PRODUCTO RESPUESTA INMUNITARIA

TENGO UNA PERRITA CON LEHISMANIA, LLEVA POCO TIEMPO CONSUMIENDO EL PRODUCTO PERO CREO QUE ES BUENO PARA ELLA, ESPERO QUE LE AYUDE APARTE DE MI CARIÑO Y AMOR, GRACIAS

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Immunokun (dogs - 270 g) Immune Response Enhancement Supplement

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