Enterokun Severe 85 g

Replenishes fecal losses of K and Cl and promotes water absorption. Severe hypokalemia can cause significant problems in cardiac function.

Replenishes fecal losses of Na and Cl and promotes water absorption.

The transport of tryptophan across the blood-brain barrier depends on the plasma concentrations of tryptophan and other large neutral amino acids (LNAA; tyrosine, phenylalanine, leucine, isoleucine, and valine), as they compete for the same transport mechanism. A high postprandial insulin level in the blood after a carbohydrate load favors the transport of tryptophan to the brain because it mediates the uptake of LNAA into muscle but not tryptophan, which is largely bound to plasma albumin, increasing the tryptophan/LNAA ratio in the blood and favoring its transport into the brain.

As a buffer salt, it helps to combat metabolic acidosis caused by fluid loss from the caudal small intestine and large intestine, which contain a higher concentration of bicarbonate than plasma. Trisodium citrate is converted into bicarbonate in the liver at a 1:3 ratio. Thus, through the citric acid cycle, one molecule of citrate consumes 3 protons and produces 3 molecules of bicarbonate.

Maintains the function and integrity of the intestinal barrier at the level of tight junctions, thus preventing the entry of antigens, toxins, and pathogenic bacteria that cause inflammation.

Improves the balance of the intestinal microbiota. Competition for nutrients, adhesion sites, and the production of antimicrobial substances (short-chain fatty acids, defensins, etc.) inhibit the proliferation of pathogenic bacteria while promoting the development of beneficial bacteria.

Prebiotic component, which means it resists digestion and reaches the colon intact where it serves as an energy source for beneficial bacteria (Lactobacillus spp, Bacteroides spp, and Bifidobacterium spp), thus stimulating their growth and/or activity. As a result of its fermentation, the production of toxic substances (ammonia and biogenic amines) decreases and the release of short-chain fatty acids (acetate, propionate, lactate, and butyrate) into the intestinal lumen increases, reducing the presence of pathogenic bacteria (E. coli and C. perfringens), thanks to the reduction of colonic pH.

They capture and eliminate pathogens from the gastrointestinal tract, as they act as analogs of receptors for type 1 fimbriae, present in gram-negative pathogenic bacteria (E. coli and Salmonella). They also stimulate the immune system, increasing IgA secretion and, therefore, local resistance to antigen invasion.

Precursor of glutamine, considered a conditionally essential amino acid, necessary during intestinal recovery. As the preferred energy substrate for rapidly proliferating cells, glutamine is necessary to maintain the integrity of the intestinal mucosa and gut-associated lymphoid tissue, thus preventing intestinal atrophy and bacterial translocation.